Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Brain : a journal of neurology
Published
Brain health concerns in former rugby players: clinical and cognitive phenotypes
Authors
Thomas D Parker, Jessica A Hain, Erin J Rooney, Karl A Zimmerman, Ying Lee, Martina Del Giovane, Neil S N Graham, Maneesh Patel, Adam Hampshire, Mathew G Wilson, Daniel Friedland, David J Sharp, Richard J Sylvester
Brain health concerns in former rugby players: clinical and cognitive phenotypes
Nature communications
Published
Proteomic analysis of Down syndrome cerebrospinal fluid compared to late-onset and autosomal dominant Alzheimer´s disease
Authors
Laia Montoliu-Gaya, Shijia Bian, Eric B Dammer, Daniel Alcolea, Mathias Sauer, Mitchell Martá-Ariza, Nicholas J Ashton, Olivia Belbin, Johannes Fuchs, Caroline M Watson, Lingyan Ping, Duc M Duong, Johanna Nilsson, Isabel Barroeta, Juan Lantero-Rodriguez, Laura Videla, Bessy Benejam, Blaine R Roberts, Kaj Blennow, Nicholas T Seyfried, Allan I Levey, María Carmona-Iragui, Johan Gobom, Alberto Lleó, Thomas Wisniewski, Henrik Zetterberg, Juan Fortea, Erik C B Johnson
Proteomic analysis of Down syndrome cerebrospinal fluid compared to late-onset and autosomal dominant Alzheimer´s disease
The Journal of frailty & aging..
Published
Associations between intrinsic capacity, plasma p-tau181 and cognitive function over a 5-year follow-up among community-dwelling older adults: a secondary analysis of the MAPT Study
Authors
Kelly Virecoulon Giudici, Philipe de Souto Barreto, Christelle Cantet, Henrik Zetterberg, Kaj Blennow, Bruno Vellas, MAPT/DSA group
Associations between intrinsic capacity, plasma p-tau181 and cognitive function over a 5-year follow-up among community-dwelling older adults: a secondary analysis of the MAPT Study
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Plasma p-tau231 in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: A cross-sectional and longitudinal cohort study
Authors
Vincent Malotaux, Nicholas J Ashton, Annika Öhrfelt, Yinghua Chen, Yi Su, Gloria Garcia-Ospina, Claudia Guzman-Martínez, Andres Villegas-Lanau, Johana Gómez-Ramirez, Margarita Giraldo-Chica, David Aguillon, Victoria Tirado, Ana Baena, Claudia Munoz, Natalia Acosta-Baena, Jeremy J Pruzin, Valentina Ghisays, Silvia Rios-Romenets, Clara Vila-Castelar, Jairo E Martínez, Averi Giudicessi, Pierre N Tariot, Henrik Zetterberg, Kaj Blennow, Eric M Reiman, Yakeel T Quiroz
Plasma p-tau231 in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: A cross-sectional and longitudinal cohort study
Resuscitation
Published
Neurofilament light chain evaluated with a new automated commercially available method for outcome prediction in out-of-hospital cardiac arrest patients
Authors
Christel Pussinen, Mikko Anttonen, Lauri Wihersaari, Marjaana Tiainen, Matti Reinikainen, Johanna Hästbacka, Henrik Zetterberg, Kaj Blennow, Kari Pulkki, Markus B Skrifvars
Neurofilament light chain evaluated with a new automated commercially available method for outcome prediction in out-of-hospital cardiac arrest patients
Cancer cell
Published
Gene context drift identifies drug targets to mitigate cancer treatment resistance
Authors
Amir Jassim, Birgit V Nimmervoll, Sabrina Terranova, Erica Nathan, Linda Hu, Jessica T Taylor, Katherine E Masih, Lisa Ruff, Matilde Duarte, Elizabeth Cooper, Gunjan Katyal, Melika Akhbari, Reuben J Gilbertson, Jennifer C Coleman, Joseph S Toker, Colton Terhune, Gabriel Balmus, Stephen P Jackson, Hailong Liu, Tao Jiang, Michael D Taylor, Kui Hua, Jean E Abraham, Mariella G Filbin, Anthony Hill, Anarita Patrizi, Neil Dani, Aviv Regev, Maria K Lehtinen, Richard J Gilbertson
Gene context drift identifies drug targets to mitigate cancer treatment resistance
Brain communications
Published
The potential dual role of tau phosphorylation: plasma phosphorylated-tau217 in newborns and Alzheimer's disease
Authors
Fernando Gonzalez-Ortiz, Jakub Vávra, Emma Payne, Bjørn-Eivind Kirsebom, Ulrika Sjöbom, Cristiano Santos, Jordi Júlvez, Kaitlin Kramer, David Zalcberg, Laia Montoliu-Gaya, Michael Turton, Peter Harrison, Ann Hellström, Henrik Zetterberg, Tormod Fladby, Marc Suárez-Calvet, Robert D Sanders, Kaj Blennow
The potential dual role of tau phosphorylation: plasma phosphorylated-tau217 in newborns and Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Associations between objective sleep metrics and brain structure in cognitively unimpaired adults: interactions with sex and Alzheimer's biomarkers
Authors
Laura Stankeviciute, Núria Tort-Colet, Ana Fernández-Arcos, Gonzalo Sánchez-Benavides, Carolina Minguillón, Karine Fauria, Sebastian Camillo Holst, Pilar Garcés, Thomas Mueggler, Henrik Zetterberg, Kaj Blennow, Álex Iranzo, Marc Suárez-Calvet, Juan Domingo Gispert, José Luis Molinuevo, Oriol Grau-Rivera, ALFA Study
Associations between objective sleep metrics and brain structure in cognitively unimpaired adults: interactions with sex and Alzheimer's biomarkers
Alzheimer's & dementia (New York, N. Y.)
Published
The impact of estimated cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline
Authors
Adam J Paulsen, Ira Driscoll, Brianne M Breidenbach, Matthew Glittenberg, Sarah R Lose, Yue Ma, Mark A Sager, Cynthia M Carlsson, Catherine L Gallagher, Bruce P Hermann, Kaj Blennow, Henrik Zetterberg, Sanjay Asthana, Sterling C Johnson, Tobey J Betthauser, Bradley T Christian, Dane B Cook, Ozioma C Okonkwo
The impact of estimated cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline
Neurology
Published
Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration
Authors
Marissa A Gogniat, Omair A Khan, Brina Ratangee, Corey J Bolton, Panpan Zhang, Dandan Liu, Kimberly R Pechman, Alexis Yates, Leslie S Gaynor, James Eaton, Amalia Peterson, Katherine A Gifford, Timothy J Hohman, Kaj Blennow, Henrik Zetterberg, Angela L Jefferson
Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Integrating visual assessments and quantification methods for tau PET staging
Authors
Yuna Gu, Jihwan Yun, Alexis Moscoso, Michael Schöll, Daeun Shin, Eun Hye Lee, Heekyong Kang, Sohyun Yim, Hyunjin Jo, Jun Pyo Kim, Sung Hoon Kang, Hee Jin Kim, Duk L Na, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Hyemin Jang, Michael W Weiner, Seung Hwan Moon, Hanna Cho, Jae Yong Choi, Kyung Rok Nam, Byung Hyun Byun, Su Yeon Park, Jeong Ho Ha, Soo Hyun Cho, Sang Won Seo, ADNI and K‐ROAD study groups
Integrating visual assessments and quantification methods for tau PET staging
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Published
Noninvasive quantification of fasciculations to track tofersen therapy in superoxide dismutase 1 amyotrophic lateral sclerosis
Authors
James Scott, Mark Crook-Rumsey, Anna Carobin, Judith Bilgorai, Gillian Kelly, Jemeen Sreedharan, Christopher Shaw, James Bashford
Noninvasive quantification of fasciculations to track tofersen therapy in superoxide dismutase 1 amyotrophic lateral sclerosis