Skip to main content
Search
Main content
Wioleta Zelek

Dr Wioleta Zelek

Emerging Leader

Targeting novel anti-complement drugs to the brain for therapy of dementia

Biography

Dr Wioleta Zelek is a UK DRI Emerging Leader with a prestigious Race Against Dementia (RAD) Fellowship – sponsored by Group Leader Prof Paul Morgan (UK DRI at Cardiff). Dr Zelek trained in Chemistry and after several years in the Biotech sector, returned to academia and undertook a PhD in Immunology, focused on the complement system. During her PhD, and Fellowships (ISSF Wellcome Trust, Health and Care Research Wales) she developed a toolbox of novel complement inhibitors, including patent protected drug candidates (PCT/EP2020/073430) and other tool reagents enabling the study of complement in animal disease models. Dr Zelek’s main goal over the course of the Fellowship project is to develop brain penetrant anti-complement drug candidates to target neuroinflammation, a critical driver of pathology in Alzheimer's disease.

News

Key publications

Schizophr Res
Published
Complement system biomarkers in first episode psychosis.
Authors
Maja Kopczynska, Wioleta Zelek, Samuel Touchard, Fiona Gaughran, Marta Di Forti, Valeria Mondelli, Robin Murray, Michael C O'Donovan, B Paul Morgan
Complement system biomarkers in first episode psychosis.

Zelek Lab

Explore the work of the Zelek Lab, focusing on developing a new approach to Alzheimer's disease therapy; brain penetrant anti-complement drug(s), providing better ways of treating Alzheimer's disease and other dementias

Microglia and astrocyte cells