Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Stem cell reports
Published
A highly efficient method to differentiate CGRP-expressing peptidergic nociceptors from human induced pluripotent stem cells
Authors
Galbha Duggal, Xinyu Li, Philippa Pettingill, Tatjana Lalic, Shailesh Kumar Gupta, Christine Flodgaard Høgsbro, Viola Volpato, Caleb Webber, Rory Bowden, Despoina Charou, Kanisa Arunasalam, Marcello Maresca, Ryan Hicks, Satyan Chintawar, M Zameel Cader
A highly efficient method to differentiate CGRP-expressing peptidergic nociceptors from human induced pluripotent stem cells
Analytical chemistry
Published
Profiling Protein Aggregate Size Using Single-Molecule Array Technology
Authors
Dorothea Böken, Yunzhao Wu, Jianli Zhang, Zengjie Xia, Paula Beltran-Lobo, Cara L Croft, Savinu Weerasekera, Amanda Heslegrave, Henrik Zetterberg, Ashvini Keshavan, Jonathan M Schott, Maria Jimenez-Sanchez, David C Duffy, David Klenerman
Profiling Protein Aggregate Size Using Single-Molecule Array Technology
Nature communications
Published
Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress
Authors
Rebecca Casterton, Aitana Martinez-Cotrina, Jodi Barnard, Eleanor Wycherley, Yanling Hu, Rhys Anderson, Sebastien Janel, Jiin Byun, Olivia Houghton, Daniel A Solomon, Juan Alcalde, Frank Lafont, Marc-David Ruepp, Frank Hirth, Bart Tummers, Yong-Yeon Cho, Gian De Nicola, Sarah Mizielinska, Manolis Fanto
Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress
Acta neuropathologica
Published
Tau368 improves p-tau diagnostic accuracy for FTLD-tau from FTLD-TDP
Authors
Przemysław R Kac, Katheryn A Q Cousins, Alicja Szadziewska, Leslie M Shaw, Michael Turton, Vivianna M Van Deerlin, Peter Harrison, Henrik Zetterberg, David A Wolk, Corey T McMillan, Douglas Galasko, Jörg Hanrieder, Edward B Lee, Hlin Kvartsberg, David J Irwin, Kaj Blennow
Tau368 improves p-tau diagnostic accuracy for FTLD-tau from FTLD-TDP
Alzheimer's & dementia (Amsterdam, Netherlands)
Published
Cerebrospinal fluid NPTX2/p-tau ratio as a biomarker for cognitive decline in neurodegenerative diseases
Authors
Bárbara Fernandes Gomes, Mathias Sauer, Laia Montoliu-Gaya, Maria Franquesa-Mullerat, Alexandre Bejanin, Daniel Alcolea, Alberto Lleó, Ignacio Illán-Gala, Juan Fortea, Kaj Blennow, Henrik Zetterberg, Johanna Nilsson, Olivia Belbin, Nicholas J Ashton
Cerebrospinal fluid NPTX2/p-tau ratio as a biomarker for cognitive decline in neurodegenerative diseases
Alzheimer's & dementia (New York, N. Y.)
Published
Aβ- and tau-associated neuroinflammatory signatures in Alzheimer's disease
Authors
Bruna Bellaver, Guilherme Povala, Marco Antônio De Bastiani, Ilaria Pola, Pamela C L Ferreira, Guilherme Bauer-Negrini, João Pedro Ferrari-Souza, Douglas T Leffa, Firoza Z Lussier, Joseph Therriault, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Riddhi Patira, Serge Gauthier, Dana L Tudorascu, Thomas K Karikari, Nicholas Ashton, Kaj Blennow, Henrik Zetterberg, Eduardo R Zimmer, Andrea L Benedet, Pedro Rosa-Neto, Tharick A Pascoal
Aβ- and tau-associated neuroinflammatory signatures in Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Emerging directions in tauopathy research
Authors
Luc Buée, Kristin R Wildsmith, Suvarna Alladi, Taylor Bertucci, Delphine Boche, Kathryn R Bowles, Adam Boxer, Jennifer Brummet, Sarah L DeVos, Kristophe Diaz, Anna Jane Dreyer, Karen Duff, Claudia Duran-Aniotz, Claire S Durrant, Kurt Farrell, Igor C Fontana, Nicolai Franzmeier, Bess Frost, Kanta Horie, Petr Kaňovský, Aimee W Kao, Simin Mahinrad, Maura Malpetti, Huw R Morris, Carla Palleis, Leonard Petrucelli, Jessica Rexach, Larisa Reyderman, Amy Rommel, James B Rowe, Sandra M Sanabria Bohórquez, Chihiro Sato, Michael Schöll, Anja Schneider, Rohan de Silva, Heather M Snyder, Lawren VandeVrede, Andrew W Varga, Jacob W Vogel, Felix L Yeh, Andrew S Yoo, Maria C Carrillo
Emerging directions in tauopathy research
BMC neurology
Published
Neurofilament light chain and glial fibrillary acidic protein as biomarkers of peripheral nervous system involvement in multiple sclerosis: diagnostic and prognostic evaluation
Authors
Alina Flintere-Flinte, Vladimirs Krutovs, Elizabete Pantelejeva, Kaj Blennow, Henrik Zetterberg, Maksims Zolovs, Viktorija Kenina
Neurofilament light chain and glial fibrillary acidic protein as biomarkers of peripheral nervous system involvement in multiple sclerosis: diagnostic and prognostic evaluation
Ticks and tick-borne diseases
Published
Cognitive outcome in relation to cerebrospinal fluid markers of neuronal and glial cell damage: A prospective study of tick-borne encephalitis
Authors
Marie Eckerström, Malin Veje, Carl Eckerström, Auksė Mickienė, Vytautas Griška, Aistė Pranckevičienė, Jolita Pakalnienė, Diana Gabrijolavičiūtė, Henrik Zetterberg, Kaj Blennow, Marie Studahl
Cognitive outcome in relation to cerebrospinal fluid markers of neuronal and glial cell damage: A prospective study of tick-borne encephalitis