Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
The Journal of cell biology
Published
The endolysosomal system in conventional and unconventional protein secretion
Authors
Eloïse Néel, Marioara Chiritoiu-Butnaru, William Fargues, Morgane Denus, Maëlle Colladant, Aurore Filaquier, Sarah E Stewart, Sylvain Lehmann, Chiara Zurzolo, David C Rubinsztein, Philippe Marin, Marie-Laure Parmentier, Julien Villeneuve
The endolysosomal system in conventional and unconventional protein secretion
Brain communications
Published
<em>Drosophila</em> appear resistant to trans-synaptic tau propagation
Authors
James H Catterson, Edmond N Mouofo, Inés López De Toledo Soler, Gillian Lean, Stella Dlamini, Phoebe Liddell, Graham Voong, Taxiarchis Katsinelos, Yu-Chun Wang, Nils Schoovaerts, Patrik Verstreken, Tara L Spires-Jones, Claire S Durrant
<em>Drosophila</em> appear resistant to trans-synaptic tau propagation
Science (New York, N.Y.)
Published
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress
Authors
Karinder K Brar, Daniel T Hughes, Jordan L Morris, Kelly Subramanian, Shivaani Krishna, Fei Gao, Lara-Sophie Rieder, Sebastian Uhrig, Joshua Freeman, Heather L Smith, Rebekkah Jukes-Jones, Edward Avezov, Jodi Nunnari, Julien Prudent, Adrian J Butcher, Giovanna R Mallucci
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Clinical Manifestations
Authors
Emma-Jane Mallas, Michael Cb David, Hanim Karakoc, Chris Ml Tsoi, Paresh A Malhotra, Gregory Scott, David J Sharp
Clinical Manifestations
medRxiv : the preprint server for health sciences
Published
The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic Interpretation
Authors
Guoqiao Wang, Yan Li, Chengjie Xiong, Yuchen Cao, Suzanne E Schindler, Eric McDade, Kaj Blennow, Oskar Hansson, Jeffrey L Dage, Clifford R Jack, Charlotte E Teunissen, Leslie M Shaw, Henrik Zetterberg, Ibanez Laura, Jigyasha Timsina, Cruchaga Carlos, DIAN-TU Study Team, Randall J Bateman
The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic Interpretation
Acta Neuropathologica Communications
Published
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype
Authors
Raphael Hesse, Maica Llavero Hurtado, Rosemary J. Jackson, Samantha L. Eaton, Abigail G. Herrmann, Marti Colom-Cadena, Makis Tzioras, Declan King, Jamie Rose, Jane Tulloch, Chris-Anne McKenzie, Colin Smith, Christopher M. Henstridge, Douglas Lamont, Thomas M. Wishart, Tara L. Spires-Jones
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype
Brain Communications
Published
Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Authors
Tyler S Saunders, Francesca E Pozzolo, Amanda Heslegrave, Declan King, Robert I. McGeachan, Maxwell P Spires-Jones, Sarah E Harris, Craig Ritchie, Graciela Muniz-Terrera, Ian J Deary, Simon R Cox, Henrik Zetterberg, Tara L. Spires-Jones
Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Frontiers in neuroscience
Published
Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach
Authors
Martina Del Giovane, Michael C B David, Magdalena A Kolanko, Anastasia Gontsarova, Thomas Parker, Adam Hampshire, David J Sharp, Paresh A Malhotra, Christopher Carswell
Methodological challenges of measuring brain volumes and cortical thickness in idiopathic normal pressure hydrocephalus with a surface-based approach