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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Brain communications
Published
Considerations for legal, ethical, and effective practice in dementia research
Authors
Michael C B David, Martina Del Giovane, Danielle Wilson, Trevor Truman, Jonathan D Huntley, Mehrunisha Suleman, Alexander Ruck Keene, Michael Parker, David J Sharp, Paresh A Malhotra
Considerations for legal, ethical, and effective practice in dementia research
ACS applied materials & interfaces
Published
Improved Imaging Surface for Quantitative Single-Molecule Microscopy
Authors
Yu P Zhang, Evgeniia Lobanova, Asher Dworkin, Martin Furlepa, Woo Suk Yang, Melanie Burke, Jonathan X Meng, Natalie Potter, Renata Lang Sala, Lakmini Kahanawita, Florence Layburn, Oren A Scherman, Caroline H Williams-Gray, David Klenerman
Improved Imaging Surface for Quantitative Single-Molecule Microscopy
Brain communications
Published
Investigation of the genetic aetiology of Lewy body diseases with and without dementia
Authors
Lesley Yue Wu, Raquel Real, Alejandro Martinez-Carrasco, Ruth Chia, Michael A Lawton, Maryam Shoai, Catherine Bresner, Cornelis Blauwendraat, Andrew B Singleton, Mina Ryten, International Lewy Body Dementia Genomics Consortium, Sonja W Scholz, Bryan J Traynor, Nigel M Williams, Michele T M Hu, Yoav Ben-Shlomo, Donald G Grosset, John Hardy, Huw R Morris
Investigation of the genetic aetiology of Lewy body diseases with and without dementia
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published
Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2
Authors
Jong-Chan Park, Jong Won Han, Woochan Lee, Jieun Kim, Sang-Eun Lee, Dongjoon Lee, Hayoung Choi, Jihui Han, You Jung Kang, Yen N Diep, Hansang Cho, Rian Kang, Won Jong Yu, Jean Lee, Murim Choi, Sun-Wha Im, Jong-Il Kim, Inhee Mook-Jung
Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2
bioRxiv : the preprint server for biology
Published
Loss of TDP-43 induces synaptic dysfunction that is rescued by <em>UNC13A</em> splice-switching ASOs
Authors
Matthew J Keuss, Peter Harley, Eugeni Ryadnov, Rachel E Jackson, Matteo Zanovello, Oscar G Wilkins, Simone Barattucci, Puja R Mehta, Marcio G Oliveira, Joanna E Parkes, Aparna Sinha, Andrés F Correa-Sánchez, Peter L Oliver, Elizabeth M C Fisher, Giampietro Schiavo, Mala Shah, Juan Burrone, Pietro Fratta
Loss of TDP-43 induces synaptic dysfunction that is rescued by <em>UNC13A</em> splice-switching ASOs
Journal of experimental & clinical cancer research : CR
Published
Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma
Authors
Daniel S K Liu, Jisce R Puik, Bhavik Y Patel, Morten T Venø, Mahrou Vahabi, Mireia Mato Prado, Jason P Webber, Eleanor Rees, Flora M Upton, Kate Bennett, Catherine Blaker, Benoit Immordino, Annalisa Comandatore, Luca Morelli, Shivan Sivakumar, Rutger-Jan Swijnenburg, Marc G Besselink, Long R Jiao, Geert Kazemier, Elisa Giovannetti, Jonathan Krell, Adam E Frampton
Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma
Brain, behavior, and immunity
Published
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression
Authors
Michael R Duggan, Gabriela T Gomez, Cassandra M Joynes, Murat Bilgel, Jingsha Chen, Nicola Fattorelli, Timothy J Hohman, Renzo Mancuso, Jenifer Cordon, Tonnar Castellano, Mary Ellen I Koran, Julián Candia, Alexandria Lewis, Abhay Moghekar, Nicholas J Ashton, Przemysław R Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Anna Martinez-Muriana, Bart De Strooper, Madhav Thambisetty, Luigi Ferrucci, Rebecca F Gottesman, Josef Coresh, Susan M Resnick, Keenan A Walker
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression
Dev Sci
Published
Cortical tracking of visual rhythmic speech by 5- and 8-month-old infants: Individual differences in phase angle relate to language outcomes up to 2 years.
Authors
Áine Ní Choisdealbha, Adam Attaheri, Sinead Rocha, Natasha Mead, Helen Olawole-Scott, Maria Alfaro E Oliveira, Carmel Brough, Perrine Brusini, Samuel Gibbon, Panagiotis Boutris, Christina Grey, Isabel Williams, Sheila Flanagan, Usha Goswami
Cortical tracking of visual rhythmic speech by 5- and 8-month-old infants: Individual differences in phase angle relate to language outcomes up to 2 years.
The Journal of physiology
Published
Bridging the gap between experimental control and ecological validity in human sensorimotor science
Authors
Jonathan Tsay, Nathan Steadman, Melanie Fleming, Mareike Gann, Irene Di Giulio, Cosima Graef, Jinpei Han, Kavindu Jayasinghe, Matthew Mitchell, Robert Chen, Kausar Raheel, Edgar Semedo, Raul Sîmpetru, Kurnia Putri Utami, Allie Williams, Ziyue Zhu, Charlotte Stagg, Shlomi Haar
Bridging the gap between experimental control and ecological validity in human sensorimotor science
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
Authors
Aurore Delvenne, Johan Gobom, Suzanne E Schindler, Mara Ten Kate, Lianne M Reus, Valerija Dobricic, Betty M Tijms, Tammie L S Benzinger, Carlos Cruchaga, Charlotte E Teunissen, Inez Ramakers, Pablo Martinez-Lage, Mikel Tainta, Rik Vandenberghe, Jolien Schaeverbeke, Sebastiaan Engelborghs, Ellen De Roeck, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Yvonne Freund-Levi, Simon Lovestone, Johannes Streffer, Frederik Barkhof, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Stephanie J B Vos
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced sample
Authors
Lianlian Du, Rebecca E Langhough, Rachael E Wilson, Ramiro Eduardo Rea Reyes, Bruce P Hermann, Erin M Jonaitis, Tobey J Betthauser, Nathaniel A Chin, Bradley Christian, Lauren Chaby, Andreas Jeromin, Guglielmo Di Molfetta, Wagner S Brum, Burak Arslan, Nicholas Ashton, Kaj Blennow, Henrik Zetterberg, Sterling C Johnson
Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced sample
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Perivascular spaces, plasma GFAP, and speeded executive function in neurodegenerative diseases
Authors
Daniela Andriuta, Julie Ottoy, Myuri Ruthirakuhan, Ginelle Feliciano, Allison A Dilliott, Robert A Hegele, Fuqiang Gao, Paula M McLaughlin, Jennifer S Rabin, Madeline Wood Alexander, Christopher J M Scott, Vanessa Yhap, Courtney Berezuk, Miracle Ozzoude, Walter Swardfager, Julia Zebarth, M Carmela Tartaglia, Ekaterina Rogaeva, David F Tang-Wai, Leanne Casaubon, Sanjeev Kumar, Dar Dowlatshahi, Jennifer Mandzia, Demetrios Sahlas, Gustavo Saposnik, Corinne E Fischer, Michael Borrie, Ayman Hassan, Malcolm A Binns, Morris Freedman, Howard Chertkow, Elizabeth Finger, Andrew Frank, Robert Bartha, Sean Symons, Henrik Zetterberg, Richard H Swartz, Mario Masellis, Sandra E Black, Joel Ramirez, ONDRI Investigators
Perivascular spaces, plasma GFAP, and speeded executive function in neurodegenerative diseases
Science translational medicine
Published
A nose for tau
Authors
Soraya Meftah, Claire S Durrant, Tara L Spires-Jones
A nose for tau