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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

The Lancet. Neurology
Published
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
Authors
Joseph Therriault, Wagner S Brum, Lydia Trudel, Arthur C Macedo, Fernando Valentim Bitencourt, Carolina Castro Martins-Pfeifer, Martin Nakouzi, Ilaria Pola, Matthew Wong, Przemysław R Kac, Ana Paula Real, Chloë Witherow, Thomas K Karikari, Alexis Moscoso, Eduardo R Zimmer, Michael Schöll, Tharick Pascoal, Andrea L Benedet, Nicholas J Ashton, Suzanne E Schindler, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
Brain : a journal of neurology
Published
Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease
Authors
Hannah de Bruin, Colin Groot, Henryk Barthel, Gérard N Bischof, Ganna Blazhenets, Ronald Boellaard, Baayla D C Boon, Matthias Brendel, David M Cash, William Coath, Gregory S Day, Bradford C Dickerson, Elena Doering, Alexander Drzezga, Christopher H van Dyck, Thilo van Eimeren, Wiesje M van der Flier, Carolyn A Fredericks, Tim D Fryer, Elsmarieke van de Giessen, Brian A Gordon, Jonathan Graff-Radford, Lea T Grinberg, Oskar Hansson, Diana A Hobbs, Merle C Hoenig, Günter Höglinger, David J Irwin, P Simon Jones, Keith A Josephs, Yuta Katsumi, Renaud La Joie, Edward B Lee, Johannes Levin, Maura Malpetti, Scott M McGinnis, Adam P Mecca, Rosaleena Mohanty, Ilya M Nasrallah, John T O'Brien, Ryan S O'Dell, Carla Palleis, Robert Perneczky, Jeffrey S Phillips, Deepti Putcha, Gil D Rabinovici, Nesrine Rahmouni, Pedro Rosa-Neto, James B Rowe, Michael Rullmann, Osama Sabri, Dorothee Saur, Andreas Schildan, Jonathan M Schott, Matthias L Schroeter, William W Seeley, Stijn Servaes, Irene Sintini, Ruben Smith, Salvatore Spina, Jenna Stevenson, Erik Stomrud, Olof Strandberg, Joseph Therriault, Pontus Tideman, Alexandra Touroutoglou, Anne E Trainer, Denise Visser, Fattin Wekselman, Philip S J Weston, Jennifer L Whitwell, David A Wolk, Keir Yong, Yolande A L Pijnenburg, Nicolai Franzmeier, Rik Ossenkoppele
Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk
Authors
Yen-Ning Huang, Shiwei Liu, Tamina Park, Soumilee Chaudhuri, Lindsey A Kuchenbecker, Minerva M Carrasquillo, Nilüfer Ertekin-Taner, Paula J Bice, Henrik Zetterberg, Kaj Blennow, Kristen Russ, Jeffrey L Dage, Kelly N H Nudelman, Carlos Cruchaga, Jared R Brosch, Martin R Farlow, David G Clark, Sunu Mathew, Frederick Unverzagt, Sujuan Gao, Sophia Wang, Liana G Apostolova, Donna M Wilcock, Tatiana Foroud, Shannon L Risacher, Andrew J Saykin, Kwangsik Nho
Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk
Nature
Published
The genomic origin of the unique chaetognath body plan
Authors
Laura Piovani, Daria Gavriouchkina, Elise Parey, Luke A Sarre, Katja T C A Peijnenburg, José María Martín-Durán, Daniel S Rokhsar, Noriyuki Satoh, Alex de Mendoza, Taichiro Goto, Ferdinand Marlétaz
The genomic origin of the unique chaetognath body plan
The European journal of neuroscience
Published
Amyloid-Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease
Authors
Robert I McGeachan, Lucy Ewbank, Meg Watt, Lorena Sordo, Alexandra Malbon, Muhammad Khalid F Salamat, Makis Tzioras, Joao Miguel De Frias, Jane Tulloch, Fiona Houston, Danièlle Gunn-Moore, Tara L Spires-Jones
Amyloid-Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease
The journal of prevention of Alzheimer's disease
Published
Blood pressure and Alzheimer's disease biomarkers in cognitively unimpaired adults: a multicenter study
Authors
Mariona Osset-Malla, Aitana Martínez-Velasco, Gonzalo Sánchez-Benavides, Mariateresa Buongiorno, Alejandro de la Sierra, Mahnaz Shekari, Carolina Minguillon, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Henrik Zetterberg, Kaj Blennow, David Vállez García, Marc Suárez-Calvet, Juan Domingo Gispert, Oriol Grau-Rivera, ALFA Study
Blood pressure and Alzheimer's disease biomarkers in cognitively unimpaired adults: a multicenter study
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology
Authors
Laia Montoliu-Gaya, Elizabeth Valeriano-Lorenzo, Nicholas J Ashton, Francisco J López-González, Juan Lantero-Rodriguez, Alicia Ruiz-González, Ana Belén Pastor, Belen Frades, María Ascensión Zea-Sevilla, Meritxell Valentí, Paloma Ruiz-Valderrey, Laura Saiz, Iván Burgueño-García, Maria José López-Martínez, Teodoro Del Ser, Gunnar Brinkmalm, Henrik Zetterberg, Alberto Rábano, Johan Gobom, Kaj Blennow, Pascual Sánchez-Juan
Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology
Alzheimer's & dementia (New York, N. Y.)
Published
More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles
Authors
Mackenzie Jarchow, Ira Driscoll, Brianne M Breidenbach, Noah Cook, Catherine L Gallagher, Sterling C Johnson, Sanjay Asthana, Bruce P Hermann, Mark A Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M Carlsson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Dane B Cook, Dena B Dubal, Ozioma C Okonkwo
More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles
medRxiv : the preprint server for health sciences
Published
The PREVENT-AD cohort: accelerating Alzheimer's disease research and treatment in Canada and beyond
Authors
Sylvia Villeneuve, Judes Poirier, John C S Breitner, Jennifer Tremblay-Mercier, Jordana Remz, Jean-Michel Raoult, Yara Yakoub, Jonathan Gallego-Rudolf, Ting Qiu, Alfonso Fajardo Valdez, Bery Mohammediyan, Mohammadali Javanray, Amelie Metz, Safa Sanami, Valentin Ourry, Alfie Wearn, Alexandre Pastor-Bernier, Manon Edde, Julie Gonneaud, Cherie Strikwerda-Brown, Christine L Tardif, Claudine J Gauthier, Maxime Descoteaux, Mahsa Dadar, Étienne Vachon-Presseau, Andree-Ann Baril, Simon Ducharme, Maxime Montembeault, Maiya R Geddes, Jean-Paul Soucy, Natasha Rajah, Robert Laforce, Christian Bocti, Christos Davatzikos, Lune Bellec, Pedro Rosa-Neto, Sylvain Baillet, Alan C Evans, D Louis Collins, M Mallar Chakravarty, Kaj Blennow, Henrik Zetterberg, R Nathan Spreng, Alexa Pichet Binette, PREVENT-AD Research Group
The PREVENT-AD cohort: accelerating Alzheimer's disease research and treatment in Canada and beyond
Alzheimer's research & therapy
Published
Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups
Authors
Heekyoung Kang, Heejin Yoo, Jungah Lee, Soyeon Yoon, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Theresa A Day, Sung Hoon Kang, Jihwan Yun, Min Young Chun, Eun Hye Lee, Jun Pyo Kim, Hee Jin Kim, Duk L Na, Hyemin Jang, Daeun Shin, Sang Won Seo, K-ROAD study group
Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published
Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease
Authors
Gordon W Blair, Ian J C MacCormick, Sarah McGrory, Tom MacGillivray, Iona Hamilton, Yulu Shi, Francesca Chappell, Michael J Thrippleton, Michael S Stringer, Fergus Doubal, Joanna M Wardlaw
Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease
European journal of nuclear medicine and molecular imaging
Published
Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles
Authors
Daeun Shin, Hyemin Jang, Heejin Yoo, Kyungmin Kim, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Eun Hye Lee, Jihwan Yun, Duk L Na, Hee Jin Kim, Sung Hoon Kang, Ko Woon Kim, Si Eun Kim, Yeo Jin Kim, Yeshin Kim, Min Young Chun, Na Yeon Jung, Soo Hyun Cho, Jun Pyo Kim, Sang Won Seo, K-ROAD study groups
Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles