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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Cell
Published

Direct observation of the interconversion of normal and toxic forms of α-synuclein.

Authors
Nunilo Cremades, Samuel I A Cohen, Emma Deas, Andrey Y Abramov, Allen Y Chen, Angel Orte, Massimo Sandal, Richard W Clarke, Paul Dunne, Francesco A Aprile, Carlos W Bertoncini, Nicholas W Wood, Tuomas P J Knowles, Christopher M Dobson, David Klenerman
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Nature
Published

Accurate whole human genome sequencing using reversible terminator chemistry.

Authors
David R Bentley, Shankar Balasubramanian, Harold P Swerdlow, Geoffrey P Smith, John Milton, Clive G Brown, Kevin P Hall, Dirk J Evers, Colin L Barnes, Helen R Bignell, Jonathan M Boutell, Jason Bryant, Richard J Carter, R Keira Cheetham, Anthony J Cox, Darren J Ellis, Michael R Flatbush, Niall A Gormley, Sean J Humphray, Leslie J Irving, Mirian S Karbelashvili, Scott M Kirk, Heng Li, Xiaohai Liu, Klaus S Maisinger, Lisa J Murray, Bojan Obradovic, Tobias Ost, Michael L Parkinson, Mark R Pratt, Isabelle M J Rasolonjatovo, Mark T Reed, Roberto Rigatti, Chiara Rodighiero, Mark T Ross, Andrea Sabot, Subramanian V Sankar, Aylwyn Scally, Gary P Schroth, Mark E Smith, Vincent P Smith, Anastassia Spiridou, Peta E Torrance, Svilen S Tzonev, Eric H Vermaas, Klaudia Walter, Xiaolin Wu, Lu Zhang, Mohammed D Alam, Carole Anastasi, Ify C Aniebo, David M D Bailey, Iain R Bancarz, Saibal Banerjee, Selena G Barbour, Primo A Baybayan, Vincent A Benoit, Kevin F Benson, Claire Bevis, Phillip J Black, Asha Boodhun, Joe S Brennan, John A Bridgham, Rob C Brown, Andrew A Brown, Dale H Buermann, Abass A Bundu, James C Burrows, Nigel P Carter, Nestor Castillo, Maria Chiara E Catenazzi, Simon Chang, R Neil Cooley, Natasha R Crake, Olubunmi O Dada, Konstantinos D Diakoumakos, Belen Dominguez-Fernandez, David J Earnshaw, Ugonna C Egbujor, David W Elmore, Sergey S Etchin, Mark R Ewan, Milan Fedurco, Louise J Fraser, Karin V Fuentes Fajardo, W Scott Furey, David George, Kimberley J Gietzen, Colin P Goddard, George S Golda, Philip A Granieri, David E Green, David L Gustafson, Nancy F Hansen, Kevin Harnish, Christian D Haudenschild, Narinder I Heyer, Matthew M Hims, Johnny T Ho, Adrian M Horgan, Katya Hoschler, Steve Hurwitz, Denis V Ivanov, Maria Q Johnson, Terena James, T A Huw Jones, Gyoung-Dong Kang, Tzvetana H Kerelska, Alan D Kersey, Irina Khrebtukova, Alex P Kindwall, Zoya Kingsbury, Paula I Kokko-Gonzales, Anil Kumar, Marc A Laurent, Cynthia T Lawley, Sarah E Lee, Xavier Lee, Arnold K Liao, Jennifer A Loch, Mitch Lok, Shujun Luo, Radhika M Mammen, John W Martin, Patrick G McCauley, Paul McNitt, Parul Mehta, Keith W Moon, Joe W Mullens, Taksina Newington, Zemin Ning, Bee Ling Ng, Sonia M Novo, Michael J O'Neill, Mark A Osborne, Andrew Osnowski, Omead Ostadan, Lambros L Paraschos, Lea Pickering, Andrew C Pike, Alger C Pike, D Chris Pinkard, Daniel P Pliskin, Joe Podhasky, Victor J Quijano, Come Raczy, Vicki H Rae, Stephen R Rawlings, Ana Chiva Rodriguez, Phyllida M Roe, John Rogers, Maria C Rogert Bacigalupo, Nikolai Romanov, Anthony Romieu, Rithy K Roth, Natalie J Rourke, Silke T Ruediger, Eli Rusman, Raquel M Sanches-Kuiper, Martin R Schenker, Josefina M Seoane, Richard J Shaw, Mitch K Shiver, Steven W Short, Ning L Sizto, Johannes P Sluis, Melanie A Smith, Jean Ernest Sohna Sohna, Eric J Spence, Kim Stevens, Neil Sutton, Lukasz Szajkowski, Carolyn L Tregidgo, Gerardo Turcatti, Stephanie Vandevondele, Yuli Verhovsky, Selene M Virk, Suzanne Wakelin, Gregory C Walcott, Jingwen Wang, Graham J Worsley, Juying Yan, Ling Yau, Mike Zuerlein, Jane Rogers, James C Mullikin, Matthew E Hurles, Nick J McCooke, John S West, Frank L Oaks, Peter L Lundberg, David Klenerman, Richard Durbin, Anthony J Smith
Accurate whole human genome sequencing using reversible terminator chemistry.
Science
Published

alpha-Synuclein locus triplication causes Parkinson's disease.

Authors
A B Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum, S Lincoln, A Crawley, M Hanson, D Maraganore, C Adler, M R Cookson, M Muenter, M Baptista, D Miller, J Blancato, J Hardy, K Gwinn-Hardy
alpha-Synuclein locus triplication causes Parkinson's disease.