Skip to main content
Search
Main content

Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Development of language composites for enhanced sensitivity to multiple plasma biomarkers
Authors
Deling He, Rebecca E Langhough, Carol Van Hulle, Kristin Basche, Erin Jonaitis, Rachael Wilson, Bruce Hermann, Henrik Zetterberg, Sterling Johnson, Kimberly D Mueller
Development of language composites for enhanced sensitivity to multiple plasma biomarkers
Journal of Alzheimer's disease : JAD
Published
Plasma soluble TREM2 is associated with plasma pTau-181 and pTau-231 in cognitively normal older adults at risk of Alzheimer's disease
Authors
Prita R Asih, Cameron W Morris, Hong Wang, Steve Pedrini, Kathryn Goozee, Simon M Laws, Pratishtha Chatterjee, Kevin Taddei, Hamid R Sohrabi, Stephanie R Rainey-Smith, Chai K Lim, Gilles J Guillemin, Thomas K Karikari, Colin L Masters, Henrik Zetterberg, Kaj Blennow, Nicholas J Ashton, Ralph N Martins
Plasma soluble TREM2 is associated with plasma pTau-181 and pTau-231 in cognitively normal older adults at risk of Alzheimer's disease
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published
Assessing post-stroke cognition in pre-clinical models: Lessons and recommendations from a multi-center study
Authors
Gaia Brezzo, Kristy A Zera, Dana E Straus, Jennifer E Goertz, Sanna H Loppi, Rachel R Crumpacker, Jennifer B Frye, Danielle A Becktel, Maria Isabel Cuartero, Alicia García Culebras, Claudia Dames, Daniel Berchtold, Jill H Fowler, Andreas Meisel, Josef Anrather, Maria Angeles Moro, Stuart M Allan, Kristian P Doyle, Marion S Buckwalter, Barry W McColl
Assessing post-stroke cognition in pre-clinical models: Lessons and recommendations from a multi-center study
BMJ open
Published
Digital App for Speech and Health Monitoring Study (DASH): protocol for a prospective longitudinal case-control observational study for developing speech datasets in neurodegenerative disorders and dementia
Authors
Johnny Tam, Christine Weaver, Amarachi Ihenacho, Judith Newton, Bruce Virgo, Steven Barrett, Jonathan Neale, David Perry, Alice Smith, Siddharthan Chandran, Oliver Watts, Suvankar Pal, DASH Consortium
Digital App for Speech and Health Monitoring Study (DASH): protocol for a prospective longitudinal case-control observational study for developing speech datasets in neurodegenerative disorders and dementia
Pituitary
Published
Brain injury biomarkers and intraoperative hypotension: associations with pituitary hormone deficiency following transsphenoidal endoscopic surgery for non-functioning pituitary adenomas
Authors
Martin Thorsson, P Trimpou, M Asztély, T Hallén, V Hantelius, K Blennow, H Zetterberg, G Johannsson, J Oras, T Skoglund
Brain injury biomarkers and intraoperative hypotension: associations with pituitary hormone deficiency following transsphenoidal endoscopic surgery for non-functioning pituitary adenomas
EJNMMI physics
Published
Performance evaluation of the nanoScan<sup>®</sup> P123S total-body PET
Authors
Dániel Réti, Carlos-Alcaide Corral, Islay Cranston, Victoria J M Reid, Kerry M O'Rourke, Timaeus E F Morgan, Axel Montagne, Maurits A Jansen, Valeria K Burianova, Andrew Sutherland, Péter Major, Kálmán Nagy, Gergő Bagaméry, Adriana A S Tavares
Performance evaluation of the nanoScan<sup>®</sup> P123S total-body PET
Scientific reports
Published
Impact of meningoencephalitis and sepsis on delirium and subsequent neurological impairment in pediatric patients: a prospective proof-of-concept biomarker and EEG study
Authors
Felix Klawitter, Johanna Hackenberg, Lena Danckert, Astrid Bertsche, Axel Petzold, Heidi A B Smith, Eugene Wesley Ely, Christian Spang, Rika Bajorat, Dagmar-Christiane Fischer, Gerd Klinkmann, Anne Körmann-Günther, Robert Fleischmann, Amanda Heslegrave, Henrik Zetterberg, Hessel Peters-Sengers, Johannes Ehler, Critical Care Consultant
Impact of meningoencephalitis and sepsis on delirium and subsequent neurological impairment in pediatric patients: a prospective proof-of-concept biomarker and EEG study
Alzheimer's research & therapy
Published
Longitudinal biomarker studies in human neuroimaging: capturing biological change of Alzheimer's pathology
Authors
Larissa Fischer, Dana Parker, Samira Maboudian, Corrina Fonseca, Claudia Tato-Fernández, Lucie Annen, Prithvi Arunachalam, Julia R Bacci, Michelle Barboure, Serena Capelli, Stamatia Karagianni, Lyduine E Collij, Paul Edison, Nick C Fox, Nicolai Franzmeier, Michel J Grothe, William J Jagust, Anne Maass, Maura Malpetti, Ross W Paterson, Aitana Sogorb-Esteve, Michael Schöll
Longitudinal biomarker studies in human neuroimaging: capturing biological change of Alzheimer's pathology
Brain : a journal of neurology
Published
Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration
Authors
Julie F H De Houwer, Elise G Dopper, Renee van Buuren, Marijke Stokkel, Liset de Boer, Tine Swartenbroekx, Pam A Boesjes, Ana Rajicic, Aitana Sogorb-Esteve, Arabella Bouzigues, Lucy L Russell, Phoebe H Foster, Eve Ferry-Bolder, John C van Swieten, Lize C Jiskoot, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Benedetta Nacmias, Markus Otto, Maxime Bertoux, Thibaud Lebouvier, Simon Ducharme, Chris R Butler, Isabelle Le Ber, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, James B Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, Henrik Zetterberg, Jonathan D Rohrer, Betty M Tijms, Yolande A L Pijnenburg, Charlotte Teunissen, Harro Seelaar
Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration
bioRxiv : the preprint server for biology
Published
<em>APOE</em> E4 Alzheimer's Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex
Authors
Louise A Huuki-Myers, Heena R Divecha, Svitlana V Bach, Madeline R Valentine, Nicholas J Eagles, Bernard Mulvey, Rahul A Bharadwaj, Ruth Zhang, James R Evans, Melissa Grant-Peters, Ryan A Miller, Joel E Kleinman, Shizhong Han, Thomas M Hyde, Stephanie C Page, Daniel R Weinberger, Keri Martinowich, Mina Ryten, Kristen R Maynard, Leonardo Collado-Torres
<em>APOE</em> E4 Alzheimer's Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex
Brain and neuroscience advances
Published
The UK National Mouse Genetics Network: Translating genetic findings using preclinical mouse models to better understand neurodevelopmental, neuropsychiatric and neurodegenerative disorders
Authors
Sevda T Boyanova, Nicholas E Clifton, Karolina Dec, Michal M Milczarek, MURIDAE Cluster, Anthony R Isles
The UK National Mouse Genetics Network: Translating genetic findings using preclinical mouse models to better understand neurodevelopmental, neuropsychiatric and neurodegenerative disorders
medRxiv : the preprint server for health sciences
Published
Genetic drivers of progression in Alzheimer's disease are distinct from disease risk
Authors
Celeste E Cohen, Shane Fernandez, Umran Yaman, Ahmad R Ehyaei, Tenielle Porter, Eleanor O'Brien, Australian Imaging Biomarkers and Lifestyle Study, Alzheimer’s Disease Neuroimaging Initiative, Paul Maruff, John A Hardy, Simon M Laws, Dervis Salih, Maryam Shoai
Genetic drivers of progression in Alzheimer's disease are distinct from disease risk
bioRxiv : the preprint server for biology
Published
Sensitivity to TDP-43 loss and degradation resistance determine cryptic exon biomarker potential
Authors
Anna-Leigh Brown, Matteo Zanovello, Alla Mikheenko, Dario Dattilo, Flaminia Pellegrini, Sam Bryce-Smith, Francesca Mattedi, Puja R Mehta, Jose Norberto S Vargas, NYGC ALS Consortium, Jack Humphrey, Matthew J Keuss, Pietro Fratta
Sensitivity to TDP-43 loss and degradation resistance determine cryptic exon biomarker potential
bioRxiv : the preprint server for biology
Published
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis
Authors
Jose Cevallos, Elena Eubanks, Sunghoo Jung, Yiming Huang, Elyse Guadagno, Neeharika Rao Suvvari, Aryan Doshi, Nitya Ravinutala, Alejandro Mosera, Nagendran Ramalingam, Arati Tripathi, Tim Bartels, Ulf Dettmer, Eleanna Kara
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis
medRxiv : the preprint server for health sciences
Published
Epigenome-Wide Association Study in Asian Cohort Identifies Novel DNA Methylation Markers for Carotid Intima-Media Thickness
Authors
Konstanze Tan, Sarah E Harris, Jane Maddock, Darwin Tay, Pritesh R Jain, HELIOS Study Team, Shi Qi Mok, Maxime Herbrard, Ulf Schminke, Can Can Xue, Liuh Ling Goh, Theresia Mina, Alexander Teumer, Weng Khong Lim, Khai Pang Leong, Khung Keong Yeo, Ching-Yu Cheng, Xueling Sim, Lee Eng Sing, Joanna M Wardlaw, Henry Völzke, Andrew Wong, Simon R Cox, Rinkoo Dalan, Abbas Dehghan, Marie Loh
Epigenome-Wide Association Study in Asian Cohort Identifies Novel DNA Methylation Markers for Carotid Intima-Media Thickness
Neuron
Published
Resolving the mysteries of brain clearance and immune surveillance.
Authors
Jonathan Kipnis, Helene Benveniste, Anne Eichmann, Jean-Leon Thomas, Daniel S Reich, Laura D Lewis, Li-Huei Tsai, Antoine Drieu, Erik N T P Bakker, Douglas H Kelley, Iben Lundgaard, Humberto Mestre, Benedikt Zott, Per Kristian Eide, Matthias J P van Osch, Susanne J van Veluw, Jeffrey Iliff, Andrew C Yang, Laura Santambrogio, Sandro Da Mesquita, Richard Daneman, Justin Rustenhoven, Steven A Goldman, Maiken Nedergaard
Resolving the mysteries of brain clearance and immune surveillance.