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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

International journal of molecular sciences
Published

A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome-The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1

Authors
Gustaf Gadd, Daniel Åberg, Alexander Wall, Henrik Zetterberg, Kaj Blennow, Katarina Jood, Christina Jern, Jörgen Isgaard, Johan Svensson, N David Åberg
A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome-The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1
Brain communications
Published

Impact of long-term white matter hyperintensity changes on mobility and dexterity

Authors
Angela C C Jochems, Susana Muñoz Maniega, Francesca M Chappell, Una Clancy, Carmen Arteaga, Daniela Jaime Garcia, Olivia K L Hamilton, Will Hewins, Rachel Locherty, Ellen V Backhouse, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Gerrish, Yajun Cheng, Xiaodi Liu, Junfang Zhang, Agniete Kampaite, Eleni Sakka, Maria Valdés Hernández, Stewart Wiseman, Michael S Stringer, Michael J Thrippleton, Fergus N Doubal, Joanna M Wardlaw
Impact of long-term white matter hyperintensity changes on mobility and dexterity
Brain communications
Published

CSF neurofilament light chain profiling and quantitation in neurological diseases

Authors
Claire A Leckey, John B Coulton, Tatiana A Giovannucci, Yingxin He, Aram Aslanyan, Rhiannon Laban, Amanda Heslegrave, Ivan Doykov, Francesca Ammoscato, Jeremy Chataway, Floriana De Angelis, Sharmilee Gnanapavan, Lauren M Byrne, Jonathan M Schott, Edward J Wild, Nicolas R Barthelémy, Henrik Zetterberg, Selina Wray, Randall J Bateman, Kevin Mills, Ross W Paterson
CSF neurofilament light chain profiling and quantitation in neurological diseases
Communications biology
Published

Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's disease

Authors
Lazaro M Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Thomas K Karikari, Nicholas J Ashton, Andréa L Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's disease
Brain : a journal of neurology
Published

Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia

Authors
Kyrah M Thumbadoo, Birger V Dieriks, Helen C Murray, Molly E V Swanson, Ji Hun Yoo, Nasim F Mehrabi, Clinton Turner, Michael Dragunow, Richard L M Faull, Maurice A Curtis, Teepu Siddique, Christopher E Shaw, Kathy L Newell, Lyndal Henden, Kelly L Williams, Garth A Nicholson, Emma L Scotter
Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia
Neuron
Published

Genome sequence analyses identify novel risk loci for multiple system atrophy

Authors
Ruth Chia, Anindita Ray, Zalak Shah, Jinhui Ding, Paola Ruffo, Masashi Fujita, Vilas Menon, Sara Saez-Atienzar, Paolo Reho, Karri Kaivola, Ronald L Walton, Regina H Reynolds, Ramita Karra, Shaimaa Sait, Fulya Akcimen, Monica Diez-Fairen, Ignacio Alvarez, Alessandra Fanciulli, Nadia Stefanova, Klaus Seppi, Susanne Duerr, Fabian Leys, Florian Krismer, Victoria Sidoroff, Alexander Zimprich, Walter Pirker, Olivier Rascol, Alexandra Foubert-Samier, Wassilios G Meissner, François Tison, Anne Pavy-Le Traon, Maria Teresa Pellecchia, Paolo Barone, Maria Claudia Russillo, Juan Marín-Lahoz, Jaime Kulisevsky, Soraya Torres, Pablo Mir, Maria Teresa Periñán, Christos Proukakis, Viorica Chelban, Lesley Wu, Yee Y Goh, Laura Parkkinen, Michele T Hu, Christopher Kobylecki, Jennifer A Saxon, Sara Rollinson, Emily Garland, Italo Biaggioni, Irene Litvan, Ileana Rubio, Roy N Alcalay, Kimberly T Kwei, Steven J Lubbe, Qinwen Mao, Margaret E Flanagan, Rudolph J Castellani, Vikram Khurana, Alain Ndayisaba, Andrea Calvo, Gabriele Mora, Antonio Canosa, Gianluca Floris, Ryan C Bohannan, Anni Moore, Lucy Norcliffe-Kaufmann, Jose-Alberto Palma, Horacio Kaufmann, Changyoun Kim, Michiyo Iba, Eliezer Masliah, Ted M Dawson, Liana S Rosenthal, Alexander Pantelyat, Marilyn S Albert, Olga Pletnikova, Juan C Troncoso, Jon Infante, Carmen Lage, Pascual Sánchez-Juan, Geidy E Serrano, Thomas G Beach, Pau Pastor, Huw R Morris, Diego Albani, Jordi Clarimon, Gregor K Wenning, John A Hardy, Mina Ryten, Eric Topol, Ali Torkamani, Adriano Chiò, David A Bennett, Philip L De Jager, Philip A Low, Wolfgang Singer, William P Cheshire, Zbigniew K Wszolek, Dennis W Dickson, Bryan J Traynor, J Raphael Gibbs, Clifton L Dalgard, Owen A Ross, Henry Houlden, Sonja W Scholz
Genome sequence analyses identify novel risk loci for multiple system atrophy
Nature reviews. Molecular cell biology
Published

Is amyloid-β a friend or foe?

Authors
Claire S Durrant
Is amyloid-β a friend or foe?
Acta Neuropathol
Published

Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics.

Authors
Nurun N Fancy, Amy M Smith, Alessia Caramello, Stergios Tsartsalis, Karen Davey, Robert C J Muirhead, Aisling McGarry, Marion H Jenkyns, Eleonore Schneegans, Vicky Chau, Michael Thomas, Sam Boulger, To Ka Dorcas Cheung, Emily Adair, Marianna Papageorgopoulou, Nanet Willumsen, Combiz Khozoie, Diego Gomez-Nicola, Johanna S Jackson, Paul M Matthews
Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics.
J Infect
Published

Population incidence and associated mortality of urinary tract infection in people living with dementia.

Authors
Helen Lai, Magdalena Kolanko, Lucia M Li, Megan E Parkinson, Niall J Bourke, Neil S N Graham, Michael C B David, Emma-Jane Mallas, Bowen Su, Sarah Daniels, Danielle Wilson, Mara Golemme, Claire Norman, Kirsten Jensen, Raphaella Jackson, Martin Tran, Paul S Freemont, David Wingfield, Tim Wilkinson, Edward W Gregg, Ioanna Tzoulaki, David J Sharp, Eyal Soreq
Population incidence and associated mortality of urinary tract infection in people living with dementia.