Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Current biology : CB
Published
The blood-brain barrier
Authors
Audrey Chagnot, Axel Montagne
The blood-brain barrier
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Predicting cognitive decline with amyloid-PET, plasma p-tau217, Aβ42/40, and p-tau217/Aβ42 in a community-based cohort - relevance for clinical trial enrollment
Authors
Dario Bachmann, Maha Wybitul, Andreas Buchmann, Christoph Gericke, Antje Saake, Sandro Studer, Katrin Rauen, Esmeralda Gruber, Kaj Blennow, Henrik Zetterberg, Roger M Nitsch, Christoph Hock, Valerie Treyer, Anton Gietl
Predicting cognitive decline with amyloid-PET, plasma p-tau217, Aβ42/40, and p-tau217/Aβ42 in a community-based cohort - relevance for clinical trial enrollment
European journal of nuclear medicine and molecular imaging
Published
Comparing and combining TSPO-PET tracers in tauopathies
Authors
Harry Crook, Nicolai Franzmeier, Nesrine Rahmouni, Johannes S Gnörich, Tim D Fryer, Young T Hong, Sebastian N Roemer-Cassiano, Carla Palleis, Alexandra Strauss, P Simon Jones, Franklin I Aigbirhio, Robert Hopewell, Boris-Stephan Rauchmann, Gassan Massarweh, Robert Perneczky, Johannes Levin, Günter U Höglinger, James B Rowe, John T O'Brien, Pedro Rosa-Neto, Matthias Brendel, Maura Malpetti
Comparing and combining TSPO-PET tracers in tauopathies
Neurology
Published
Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease
Authors
David López-Martos, Marc Suárez-Calvet, Marta Milà-Alomà, Juan Domingo Gispert, Gemma Salvadó, Anna Brugulat-Serrat, Mahnaz Shekari, Carolina Minguillon, Henrik Zetterberg, Kaj Blennow, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides, ALFA study
Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease
Molecular neurodegeneration
Published
Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study
Authors
Mariana I Muñoz-García, Yuetiva Deming, Ferran Lugo-Hernández, Sterling Johnson, Sanjay Asthana, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Cynthia Carlsson, Ozioma C Okonkwo, David Pérez-Martinez, Alberto Villarejo-Galende, Kaj Blennow, Marc Suárez-Calvet, Henrik Zetterberg, Barbara B Bendlin, Estrella Morenas-Rodríguez
Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
Authors
Eleonora M Vromen, Senne B Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J B Vos, Mikel Tainta, Yvonne Freund-Levi, Lutz Frölich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J van der Lee, Philip Scheltens, Yolande A L Pijnenburg, Wiesje M van der Flier, Charlotte E Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
Molecular neurodegeneration
Published
Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways
Authors
Bjørn-Eivind Kirsebom, Johanna Nilsson, Ellen Vromen, Peter Mikael Arnesen, Atle Bjørnerud, Ann Brinkmalm, Geir Bråthen, Gøril Rolfseng Grøntvedt, Jonas Jarholm, Kaja Nordengen, Lene Pålhaugen, Per Selnes, Nikias Siafarikas, Ragnhild Eide Skogseth, Sandra Tecelão, Knut Waterloo, Panpan You, Henrik Zetterberg, Dag Aarsland, Betty Tijms, Pieter Jelle Visser, Kaj Blennow, Tormod Fladby
Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways
Nature cell biology
Published
Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome
Authors
Rabia R Khawaja, Ernesto Griego, Kristen Lindenau, Asma Salek, Jessica Gambardella, Aurora Scrivo, Hannah R Monday, Mathieu Bourdenx, Jesús Madero-Pérez, Zohaib N Khan, Bhakti Chavda, Ronald Cutler, Sarah Graff, Simone Sidoli, Gaetano Santulli, Laura Santambrogio, Inmaculada Tasset, Susmita Kaushik, Li Gan, Pablo E Castillo, Ana Maria Cuervo
Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome
Schizophrenia research
Published
The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia
Authors
Maria E Dimitriades, Eve Schumacher, Janani Arudchelvam, Sara Fattinger, Salome Kurth, Fiona Pugin, Flavia Wehrle, Valeria Jaramillo, Carina Volk, Sven Leach, Ashura Buckley, David I Driver, Andjela Markovic, Judith L Rapoport, Leila Tarokh, Reto Huber, Miriam Gerstenberg
The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia