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Group Leaders

Heads of our research labs

Our Group Leaders are the driving force behind UK DRI research. Internationally recognised scientists lead independent research teams, bringing diverse expertise and innovative approaches to the field of dementia. From established leaders in the field to rising stars, our Group Leaders collaborate across disciplines and centres to tackle the most pressing questions in neurodegeneration, fostering a dynamic and productive research environment.

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John Hardy

Prof Sir John Hardy

Group Leader

UK DRI at UCL

Harnessing genetics to build a better understanding of dementia

Learn more Prof Sir John Hardy
Philip Hasel

Dr Philip Hasel

Group Leader

UK DRI at Edinburgh

Deciphering the role of astrocytes at brain borders in neurodegeneration

Learn more Dr Philip Hasel
Soyon Hong

Dr Soyon Hong

Group Leader

UK DRI at UCL

Dissecting pathways by which microglia contribute to region-specific synapse dysfunction in neurodegeneration

Learn more Dr Soyon Hong
David Hunt

Dr David Hunt

Group Leader

UK DRI at Edinburgh

Investigating how innate immune activation causes damage to the microvasculature of the brain

Learn more Dr David Hunt
Adrian Isaacs

Prof Adrian Isaacs

Group Leader

UK DRI at UCL

Deciphering the fundamental molecular causes of frontotemporal dementia and ALS

Learn more Prof Adrian Isaacs
David Klenerman

Prof Sir David Klenerman

Group Leader

UK DRI at Cambridge

Determining how protein clumps form, damage the brain and change as the different neurodegenerative diseases develop to know which ones to target for therapies

Learn more Prof Sir David Klenerman
Julija Krupic profile

Dr Julija Krupic

Group Leader

UK DRI at UCL

Understanding early changes in neuron-glia circuits in Alzheimer’s disease

Learn more Dr Julija Krupic
Sarah Marzi profile

Dr Sarah Marzi

Group Leader

UK DRI at King's

Investigating how epigenetics regulates biological mechanisms in health and disease

Learn more Dr Sarah Marzi
Tom Massey

Dr Tom Massey

Group Leader

UK DRI at Cardiff

Using recent genetic discoveries to develop new drug targets for Huntington's disease

Learn more Dr Tom Massey
Paul Matthews

Prof Paul Matthews

Group Leader

UK DRI at Imperial

Exploring neuronal vulnerability and genetic risk variants in Alzheimer’s progression

Learn more Prof Paul Matthews
Barry McColl

Dr Barry McColl

Group Leader

UK DRI at Edinburgh

Investigating the role of microglia in neurodegenerative disease

Learn more Dr Barry McColl
Will McEwan

Prof Will McEwan

Group Leader

UK DRI at Cambridge

Deciphering the mechanisms of tau accumulation and exploring new methods for treatment of tauopathies

Learn more Prof Will McEwan

Labs

Led by our Group Leaders and Emerging Leaders, our Labs are dynamic hubs of innovation, bringing together researchers at all career stages to investigate the fundamental mechanisms of dementia and associated neurodegenerative conditions. 

Woman looking down a microscope