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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts
Authors
Veerle van Gils, Willemijn J Jansen, Wiesje M van der Flier, Pablo Martinez-Lage, Jakub Hort, Inez H G B Ramakers, Olivier Rouaud, Markku Laakso, Sebastiaan Engelborghs, Julius Popp, Alberto Lleó, Anders Wallin, Magda Tsolaki, Charlotte E Teunissen, Rik Vandenberghe, Yvonne Freund-Levi, Lutz Frölich, Henrik Zetterberg, Johannes Streffer, Simon Lovestone, Justine Moonen, Argonde van Harten, Katerina Veverová, Nienke Legdeur, Anouk den Braber, Daniel Damian, Anette Hall, Janita Bralten, Giuseppe Fanelli, Barbara Franke, Geert Poelmans, Monica Bulló, Susana Jimenez-Murcia, Fernando Fernandez-Arande, Jordi Salas Salvadó, Søren Dalsgaard, Pieter Jelle Visser, Stephanie J B Vos
The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts
Imaging neuroscience (Cambridge, Mass.)
Published
Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age
Authors
Mathijs B J Dijsselhof, Candace Moore, Saba Amiri, Mervin Tee, Saima Hilal, Christopher Chen, Bert-Jan H van den Born, Wibeke Nordhøy, Ole A Andreassen, Lars T Westlye, Nishi Chaturvedi, Alun D Hughes, David M Cash, Jonathan M Schott, Carole H Sudre, Frederik Barkhof, Joost P A Kuijer, Francesca Biondo, James H Cole, Henk J M M Mutsaerts, Jan Petr
Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age
Nature communications
Published
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics
Authors
Yuki Kamijo, Philipp Mächler, Natalie Ness, Cong Quang Vu, Tsukasa Kusakizako, Jamsad Mannuthodikayil, Zaneta Ku, Marc Boisvert, Ekaterina Grebenik, Ikumi Miyazaki, Rina Hashizume, Haruaki Sato, Rui Liu, Yukiko Hori, Taisuke Tomita, Tetsuro Katayama, Akihiro Furube, Gabriela Caraveo, Marie-Eve Paquet, Mikhail Drobizhev, Osamu Nureki, Satoshi Arai, Marco Brancaccio, Robert E Campbell, David Kleinfeld, Yusuke Nasu
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics
Journal of neuroinflammation
Published
TSPO contributes to neuropathology and cognitive deficits in Alzheimer's disease
Authors
Kelly Ceyzériat, Aurélien M Badina, Laurene Abjean, Léa Meyer, Farha Bouteldja, Marta Balkota, Quentin Amossé, Oriane Prudhomme, Ryan J Middleton, Guo-Jun Liu, Richard B Banati, Thomas Zilli, Aurelien Lathuiliere, David Owen, Pierre Maechler, Valentina Garibotto, Stergios Tsartsalis, Philippe Millet, Benjamin B Tournier
TSPO contributes to neuropathology and cognitive deficits in Alzheimer's disease
Nature neuroscience
Published
Falling asleep follows a predictable bifurcation dynamic
Authors
Junheng Li, Anastasia Ilina, Robert Peach, Tianyu Wei, Edward Rhodes, Valeria Jaramillo, Ines R Violante, Mauricio Barahona, Derk-Jan Dijk, Nir Grossman
Falling asleep follows a predictable bifurcation dynamic
Journal of Alzheimer's disease : JAD
Published
Plasma p-tau<sub>217</sub> correlates strongly with cerebrospinal fluid Aβ<sub>42</sub> and increases over a ten-year period in amyloid-positive, non-demented very old men
Authors
Elisabeth Hellquist, Shorena Janelidze, Bodil Weidung, Kristin Franzon, Vilmantas Giedraitis, Martin Ingelsson, Divya Bali, Vilma Velickaite, Henrik Zetterberg, Oskar Hansson, Lena Kilander
Plasma p-tau<sub>217</sub> correlates strongly with cerebrospinal fluid Aβ<sub>42</sub> and increases over a ten-year period in amyloid-positive, non-demented very old men
Alzheimer's research & therapy
Published
CT-derived brain volumes and plasma p-Tau217 for risk stratification of amyloid positivity in early-stage Alzheimer's disease
Authors
Sohyun Yim, Seongbeom Park, Kyoung Yoon Lim, Heekyoung Kang, Daeun Shin, Hyemin Jang, Michael Weiner, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Sung Hoon Kang, Jihwan Yun, Minyoung Chun, Eunjoo Kim, Heejin Kim, Duk L Na, Jun Pyo Kim, Sang Won Seo, Kichang Kwak, K-ROAD study
CT-derived brain volumes and plasma p-Tau217 for risk stratification of amyloid positivity in early-stage Alzheimer's disease
ACS central science
Published
Enzyme Activity-Based Genome-wide Screening for Modifiers of Lysosomal Glucocerebrosidase Uncovers Candidate Risk Factors for Parkinson's Disease
Authors
Vinod Udayar, Pierre-André Gilormini, Julien Bryois, Alexandra Gehrlein, Xi Chen, Stephanie Sonea, Sha Zhu, Matthew C Deen, Nadia Anastasi, Alan E Murphy, Nathan Skene, Manuela M X Tan, Jon-Anders Tunold, Filip Roudnicky, Wilma D J van de Berg, Lasse Pihlstrøm, David J Vocadlo, Ravi Jagasia
Enzyme Activity-Based Genome-wide Screening for Modifiers of Lysosomal Glucocerebrosidase Uncovers Candidate Risk Factors for Parkinson's Disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Contactless longitudinal monitoring in the home characterizes aging and Alzheimer's disease-related night-time behavior and physiology
Authors
Eyal Soreq, Magdalena A Kolanko, CRT group, Kiran K G Ravindran, Ciro Della Monica, Victoria Revell, Sarah Daniels, Anna Joffe, Helen Lai, Mara Golemme, Martina Del Giovane, Chloe Walsh, David Wingfield, Ramin Nilforooshan, Marie-Ange Stefanos, Benjamin Vittrant, Paul de Villèle, Derk-Jan Dijk, David J Sharp
Contactless longitudinal monitoring in the home characterizes aging and Alzheimer's disease-related night-time behavior and physiology
Nature communications
Published
Distinct spatiotemporal patterns of white matter hyperintensity progression
Authors
Jinyong Chung, Gilsoon Park, Wi-Sun Ryu, Dawid Schellingerhout, Hang-Rai Kim, Dong-Seok Gwak, Elizabeth Haddad, Neda Jahanshad, Beom Joon Kim, Keun-Sik Hong, Hyerin Oh, Sang-Wuk Jeong, Joon-Tae Kim, Man Seok Park, Kang-Ho Choi, Kyungbok Lee, Tai Hwan Park, Sang-Soon Park, Jong-Moo Park, Kyusik Kang, Kyung-Ho Yu, Mi Sun Oh, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Moon-Ku Han, Yong-Jin Cho, Byung-Chul Lee, Philip M Bath, Joanna M Wardlaw, Hee-Joon Bae, Hosung Kim, Dong-Eog Kim
Distinct spatiotemporal patterns of white matter hyperintensity progression
International journal of stroke : official journal of the International Stroke Society
Published
Intravenous thrombolysis in patients with acute ischemic stroke and cerebral microbleeds: results from the ENCHANTED trial
Authors
Zien Zhou, Yilun Ge, Sohei Yoshimura, Takako Torii-Yoshimura, Yuki Sakamoto, Xiaoqiu Liu, Cheryl Carcel, Xiaoying Chen, Leibo Liu, Mark Parsons, Grant Mair, Richard Lindley, Joanna Wardlaw, Anderson Craig, Candice Delcourt
Intravenous thrombolysis in patients with acute ischemic stroke and cerebral microbleeds: results from the ENCHANTED trial