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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Cell reports
Published
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
Authors
Benedikt V Hölbling, Yashica Gupta, Paolo M Marchi, Magda L Atilano, Michael Flower, Enric Ureña, Rajkumar A Goulden, Hannah K Dobbs, Eszter Katona, Alla Mikheenko, Ashling Giblin, Ali Raza Awan, Chloe L Fisher-Ward, Niamh O'Brien, Deniz Vaizoglu, Liam Kempthorne, Katherine M Wilson, Lauren M Gittings, Mireia Carcolé, Marc-David Ruepp, Sarah Mizielinska, Linda Partridge, Pietro Fratta, Sarah J Tabrizi, Bhuvaneish T Selvaraj, Siddharthan Chandran, Emma Armstrong, Paul Whiting, Adrian M Isaacs
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
BMC nephrology
Published
Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate
Authors
Torunn Axelsson, Henrik Zetterberg, Kaj Blennow, Burak Arslan, Nicholas J Ashton, Markus Axelsson, Maria K Svensson, Aso Saeed, Gregor Guron
Plasma concentrations of neurofilament light, p-Tau231 and glial fibrillary acidic protein are elevated in patients with chronic kidney disease and correlate with measured glomerular filtration rate
JAMA network open
Published
Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers
Authors
Sung Hoon Kang, Eun Hye Lee, Young Ju Kim, Hyemin Jang, Daeun Shin, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Jihwan Yun, Hee Jin Kim, Duk L Na, Jun Pyo Kim, Sang Won Seo
Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers
EBioMedicine
Published
Blood-brain barrier injury and neuroinflammation in pre-eclampsia and eclampsia
Authors
Valentina Bucher, Owen T Herrock, Sonja Schell, Jacqui Visser, Henrik Imberg, Jonathan Burke, Henrik Zetterberg, Kaj Blennow, Susan P Walker, Stephen Tong, Joakim Ek, Catherine Cluver, Lina Bergman
Blood-brain barrier injury and neuroinflammation in pre-eclampsia and eclampsia
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Plasma GFAP for populational enrichment of clinical trials in preclinical Alzheimer's disease
Authors
Bruna Bellaver, Guilherme Povala, Pamela C L Ferreira, Guilherme Bauer-Negrini, Firoza Z Lussier, Douglas T Leffa, João Pedro Ferrari-Souza, Matheus S Rodrigues, Livia Amaral, Markley S Oliveira, Carolina Soares, Andreia Rocha, Pampa Saha, Nesrine Rahmouni, Arthur Macedo, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jesse Klostranec, Maxime Montembeault, Andréa L Benedet, Nicholas J Ashton, Rebecca Langhough Koscik, Tobey J Betthauser, Brad T Christian, Rachael Wilson, Gallen Triana-Baltzer, Paolo Vitali, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Thomas K Karikari, Dana Tudorascu, Eduardo R Zimmer, Sterling Johnson, Pedro Rosa-Neto, Tharick A Pascoal
Plasma GFAP for populational enrichment of clinical trials in preclinical Alzheimer's disease
Molecular neurodegeneration
Published
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'
Authors
Sophia Weiner, Mathias Sauer, Laia Montoliu-Gaya, Andrea L Benedet, Nicholas J Ashton, Fernando Gonzalez-Ortiz, Joel Simrén, Nesrine Rahmouni, Cecile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Ville Leinonen, Tuomas Rauramaa, Mikko Hiltunen, Pedro Rosa-Neto, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'
medRxiv : the preprint server for health sciences
Published
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness
Authors
Devendra Meena, Jian Huang, Marjan Zare, Natalie R Hasbani, Boua Palwendé Romuald, Rima Mustafa, Sander W van der Laan, Huichun Xu, James G Terry, Joshua C Bis, Deepti Jain, Nicholette D Palmer, Nancy Heard-Costa, Yuan-I Min, Xiuqing Guo, Jie Yao, Kent D Taylor, Jingyi Tan, Juan Peralta, Alexandre C Pereira, Alyna Khan, Ananyo Choudhury, Anne B Newman, Anny H Xiang, Aroon Hingorani, Barry I Freedman, Christopher J O'Donnell, Claudia Giambartolomei, David M Herrington, David R Jacobs, Derek Klarin, Fei Fei Wang, Gerardo Heiss, HarshaVardhan Doddapaneni, Howard N Hodis, Jai Broome, James G Wilson, Jean-Tristan Brandenburg, John Blangero, Jose E Krieger, Josh D Smith, Karine A Viaud-Martinez, Kathleen A Ryan, Leslie A Lange, May E Montasser, Michael C Mahaney, Michal Mokry, Myriam Fornage, Patricia Munroe, Richard A Gibbs, Russell P Tracy, Ryan W Kim, Scott M Damrauer, Stephen S Rich, Willa A Hsueh, Yii-Der Ida Chen, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, The Million Veteran Program (MVP), TOPMed Atherosclerosis Working Group, Alanna C Morrison, Braxton D Mitchell, John Jeffrey Carr, Bruce M Psaty, Donald W Bowden, Ramachandran S Vasan, Adolfo Correa, Wendy S Post, Mark O Goodarzi, Leslie J Raffel, Joanne E Curran, Michele Ramsay, Jerome I Rotter, Paul Elliott, Nora Franceschini, Paul S de Vries, Ioanna Tzoulaki, Abbas Dehghan
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness
Brain : a journal of neurology
Published
Altered T-cell reactivity in the early stages of Alzheimer's disease
Authors
Chiara Rickenbach, Anna Mallone, Lars Häusle, Larissa Frei, Sarina Seiter, Colin Sparano, Tunahan Kirabali, Kaj Blennow, Henrik Zetterberg, Maria Teresa Ferretti, Luka Kulic, Christoph Hock, Roger M Nitsch, Valerie Treyer, Anton Gietl, Christoph Gericke
Altered T-cell reactivity in the early stages of Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias
Authors
Ramiro Eduardo Rea Reyes, Rachael E Wilson, Rebecca E Langhough, Rachel L Studer, Erin M Jonaitis, Julie E Oomens, Elizabeth M Planalp, Barbara B Bendlin, Nathaniel A Chin, Sanjay Asthana, Henrik Zetterberg, Sterling C Johnson
Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias