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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Science advances
Published
Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration
Authors
Michael R Duggan, Shuojia Yang, Gabriela T Gomez, Yuhan Cui, Ana W Capuano, Jingsha Chen, Zhijian Yang, Junhao Wen, Guray Erus, Shannon M Drouin, David Zweibaum, Qu Tian, Julián Candia, Murat Bilgel, Alexandria Lewis, Abhay Moghekar, Nicholas J Ashton, Przemysław R Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Brion S Maher, Adam P Spira, Logan Dumitrescu, Timothy J Hohman, Rebecca F Gottesman, Christos Davatzikos, David A Bennett, Josef Coresh, Luigi Ferrucci, Susan M Resnick, Robert Yolken, Keenan A Walker
Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference
Authors
Bess Frost, James B Rowe, Rufus O Akinyemi, Jose F Abisambra, Nicholas J Ashton, Matthias Brendel, Luc Buée, David Butler, Maria C Carrillo, Peter Chung, Claire D Clelland, Sarah L DeVos, Kristophe Diaz, Rebecca M Edelmayer, Fanny M Elahi, Ratnavalli Ellajosyula, Colin Ewen, Igor Camargo Fontana, Marie-Christine Galas, Oskar Hansson, Günter Höglinger, Kanta Horie, Agustín Ibanez, Linde Jacobs, Mahmoud B Maina, Maura Malpetti, Eric McDade, Will McEwan, Laia Montoliu-Gaya, Catherine J Mummery, Miranda E Orr, Jonathan D Rohrer, Amy Rommel, Carlos Sastre, Tara L Spires-Jones, Boon Lead Tee, Tim J Viney, Jamie M Walker, Susanne Wegmann, Kristin Wildsmith, Ravi Yadav, Simin Mahinrad, Claire Sexton
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Repeated plasma p-tau217 measurements to monitor clinical progression heterogeneity
Authors
Bjørn-Eivind Kirsebom, Fernando Gonzalez-Ortiz, Sinthujah Vigneswaran, Geir Bråthen, Ragnhild Eide Skogseth, Berglind Gísladóttir, Peter Harrison, Jonas Alexander Jarholm, Lene Pålhaugen, Arvid Rongve, Per Selnes, Betty Tjims, Michael Turton, Argonde C Van Harten, Knut Waterloo, Henrik Zetterberg, Tormod Fladby, Kaj Blennow
Repeated plasma p-tau217 measurements to monitor clinical progression heterogeneity
JMIR aging
Published
Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study
Authors
Victoria Grace Gabb, Jonathan Blackman, Hamish Morrison, Haoxuan Li, Adrian Kendrick, Nicholas Turner, Rosemary Greenwood, Bijetri Biswas, Amanda Heslegrave, Elizabeth Coulthard
Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study
Neurology
Published
Association of Self-Reported Sleep Metrics With Imaging Markers of Small Vessel Disease and Cognition in Patients With TIA or Mild Stroke
Authors
Dillys Xiaodi Liu, Mary Sau-Man Ip, David Chi-Leung Lam, Francesca M Chappell, Una Clancy, Daniela Jaime Garcia, Carmen Arteaga-Reyes, Maria Del C Valdés Hernández, Michael Thrippleton, Michael S Stringer, Yajun Cheng, Junfang Zhang, Fergus Doubal, Gary Kui Kai Lau, Joanna M Wardlaw
Association of Self-Reported Sleep Metrics With Imaging Markers of Small Vessel Disease and Cognition in Patients With TIA or Mild Stroke
Brain communications
Published
Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker
Authors
Juliana E Gentile, Christina N Heiss, Taylor L Corridon, Meredith A Mortberg, Stefanie Fruhwürth, Kenia Guzman, Lana Grötschel, Laia Montoliu-Gaya, Kwan Chan, Neil C Herring, Timothy Janicki, Rajaa Nhass, Janani Manavala Sarathy, Brian Erickson, Ryan Kunz, Alison Erickson, Craig Braun, Katherine T Henry, Lynn Bry, Steven E Arnold, Eric Vallabh Minikel, Henrik Zetterberg, Sonia M Vallabh
Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker
Nature communications
Published
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease
Authors
Kitty B Murphy, Di Hu, Leen Wolfs, Susan K Rohde, Gonzalo Leguía Fauró, Ivana Geric, Renzo Mancuso, Bart De Strooper, Sarah J Marzi
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease
EBioMedicine
Published
A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer's disease
Authors
Armand González-Escalante, Marta Milà-Alomà, Wagner S Brum, Nicholas J Ashton, Paula Ortiz-Romero, Mahnaz Shekari, Marta Del Campo, Federica Anastasi, Clara Quijano-Rubio, Gwendlyn Kollmorgen, Carolina Minguillón, Gonzalo Sánchez-Benavides, Oriol Grau-Rivera, Juan Domingo Gispert, Henrik Zetterberg, Natalia Vilor-Tejedor, Kaj Blennow, Marc Suárez-Calvet
A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
The performance of plasma p-tau217 in Black middle-aged and older adults
Authors
Gilda E Ennis, Derek Norton, Rebecca E Langhough, Diane C Gooding, Fabu P Carter, Rachael Wilson, Megan Zuelsdorff, Shenikqua Bouges, Sanjay Asthana, Sterling C Johnson, Henrik Zetterberg, Carey E Gleason
The performance of plasma p-tau217 in Black middle-aged and older adults
The American journal of clinical nutrition
Published
The effects of the Multicultural Healthy Diet on cognitive decline & Alzheimer's disease risk: A randomized controlled trial in middle-aged adults
Authors
Yasmin Mossavar-Rahmani, Noorie Hyun, Jonathan G Hakun, Mindy J Katz, Jelena M Pavlovic, Henrik Zetterberg, Zheng Wang, Jasper B Yang, Judith Wylie-Rosett, James R Hebert, Martin J Sliwinski, Pamela A Shaw
The effects of the Multicultural Healthy Diet on cognitive decline & Alzheimer's disease risk: A randomized controlled trial in middle-aged adults
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease
Authors
Haiyan Liu, Quoc Bui, Jason Hassenstab, Brian A Gordon, Tammie L S Benzinger, Jigyasha Timsina, Yun Ju Sung, Celeste Karch, Alan E Renton, Alisha Daniels, John C Morris, Chengjie Xiong, Laura Ibanez, Richard J Perrin, Jorge J Llibre-Guerra, Gregory S Day, Charlene Supnet-Bell, Xiong Xu, Sarah B Berman, Jasmeer P Chhatwal, Takeshi Ikeuchi, Kensaku Kasuga, Yoshiki Niimi, Edward D Huey, Peter R Schofield, William S Brooks, Natalie S Ryan, Mathias Jucker, Christoph Laske, Johannes Levin, Jonathan Vöglein, Jee Hoon Roh, Francisco Lopera, Randall J Bateman, Carlos Cruchaga, Eric M McDade, For DIAN study team
Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease