UKDRI
Glia
Astrocytes on the blood vessel

People

Members of the UK DRI Glia thematic network

Researchers at a poster session

The UK DRI Glia theme meeting in York in 2024

The UK DRI Glia Thematic network is led by Dr Blanca Díaz-Castro (UK DRI at Edinburgh) and Professor Anna Williams (UK DRI at Edinburgh). The network is managed by Dr Helen Brooks (UK DRI Core Team) and has an Early Career Researcher (ECR) steering group to coordinate ECR activities.

The strengths and expertise of this theme include studying glia in the context of:

  • Stem cell derived models
  • Bioinformatic approaches
  • Molecular and cellular mechanisms
  • Neuronal-glial interactions
  • Synapse biology and circuitry
  • Neuro-glia-vascular unit and blood brain barrier
  • Biomarkers
Giles Hardingham

Prof Giles Hardingham

Centre Director

UK DRI at Edinburgh

Studying astrocytes to better understand their role in helping maintain a healthy brain

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John Hardy

Prof Sir John Hardy

Group Leader

UK DRI at UCL

Harnessing genetics to build a better understanding of dementia

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Philip Hasel

Dr Philip Hasel

Group Leader

UK DRI at Edinburgh

Deciphering the role of astrocytes at brain borders in neurodegeneration

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Soyon Hong

Dr Soyon Hong

Group Leader

UK DRI at UCL

Dissecting pathways by which microglia contribute to region-specific synapse dysfunction in neurodegeneration

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David Klenerman

Prof Sir David Klenerman

Group Leader

UK DRI at Cambridge

Determining how protein clumps form, damage the brain and change as the different neurodegenerative diseases develop to know which ones to target for therapies

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Sarah Marzi profile

Dr Sarah Marzi

Group Leader

UK DRI at King's

Investigating how epigenetics regulates biological mechanisms in health and disease

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Paul Matthews

Prof Paul Matthews

Group Leader

UK DRI at Imperial

Exploring neuronal vulnerability and genetic risk variants in Alzheimer’s progression

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Barry McColl

Dr Barry McColl

Group Leader

UK DRI at Edinburgh

Investigating the role of microglia in neurodegenerative disease

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Veronique Miron

Dr Veronique Miron

Group Leader

UK DRI at Edinburgh

Using human brain tissue analysis and experimental modelling to understand how myelin changes with ageing and dementia

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Axel Montagne

Dr Axel Montagne

Group Leader

UK DRI at Edinburgh

Exploring the link between cerebrovascular and inflamm-ageing to neurodegeneration and dementia

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Sophie Morse

Dr Sophie Morse

Emerging Leader

UK DRI at Imperial

Deploying focused ultrasound technologies to stimulate glia to treat dementia

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Profile picture of Alexi Nott

Dr Alexi Nott

Group Leader

UK DRI at Imperial

Investigating how the epigenome regulates cell type specific gene expression in ageing-related brain disorders

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